A multiscale modeling approach to glioma invasion with therapy
- We consider the multiscale model for glioma growth introduced in a previous work and extend it to account for therapy effects. Thereby, three treatment strategies involving surgical resection, radio-, and chemotherapy are compared for their efficiency. The chemotherapy relies on inhibiting the binding of cell surface receptors to the surrounding tissue, which impairs both migration and proliferation.
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| Author: | Alexander Hunt, Christina Surulescu |
|---|---|
| URN: | urn:nbn:de:hbz:386-kluedo-40487 |
| Document Type: | Preprint |
| Language of publication: | English |
| Date of Publication (online): | 2015/04/08 |
| Year of first Publication: | 2015 |
| Publishing Institution: | Technische Universität Kaiserslautern |
| Date of the Publication (Server): | 2015/04/08 |
| Page Number: | 17 |
| Faculties / Organisational entities: | Kaiserslautern - Fachbereich Mathematik |
| DDC-Cassification: | 5 Naturwissenschaften und Mathematik / 510 Mathematik |
| Licence (German): |  Standard gemäß KLUEDO-Leitlinien vom 13.02.2015 |